{"id":33,"date":"2026-08-22T06:09:01","date_gmt":"2026-08-22T06:09:01","guid":{"rendered":"https:\/\/naturavitalis.blog.rankrogic.com\/dementia-drug-development-neuroscience-history\/"},"modified":"2026-08-24T00:18:12","modified_gmt":"2026-08-24T00:18:12","slug":"dementia-drug-development-neuroscience-history","status":"publish","type":"post","link":"https:\/\/naturavitalis.blog.rankrogic.com\/dementia-drug-development-neuroscience-history\/","title":{"rendered":"\uce58\ub9e4 \uce58\ub8cc\uc81c\ub294 \uc5b4\ub5bb\uac8c \ud0c4\uc0dd\ud588\uc744\uae4c? \ub1cc\uacfc\ud559\uc758 \uc5ed\uc0ac\uc640 \uc6b0\ub9ac\uac00 \uc54c\uc544\uc57c \ud560 \uac83\ub4e4"},"content":{"rendered":"<h2>\uce58\ub9e4 \uce58\ub8cc\uc81c, \ud558\ub8e8\uc544\uce68\uc5d0 \ud0c4\uc0dd\ud558\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4<\/h2>\n<p>\uce58\ub9e4 \uce58\ub8cc\uc81c\ub294 \ub2e8\uc21c\ud788 \uc5f0\uad6c\uc18c\uc5d0\uc11c \ubc1c\uacac\ub41c \ubb3c\uc9c8\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc218\uc2ed \ub144\uac04 \uc218\ucc9c \uba85\uc758 \uacfc\ud559\uc790\uac00 \uc2e4\ud328\ub97c \uac70\ub4ed\ud558\uba70 \uc313\uc544 \uc62c\ub9b0 \ub1cc\uacfc\ud559\uc758 \uc5ed\uc0ac \uc18d\uc5d0\uc11c \ube44\ub85c\uc18c \ud0c4\uc0dd\ud55c \uacb0\uacfc\ubb3c\uc785\ub2c8\ub2e4. \uc624\ub298\uc740 \uadf8 \uae34 \uc5ec\uc815\uc744 \ud568\uaed8 \uc0b4\ud3b4\ubcf4\uba74\uc11c, \uc6b0\ub9ac \ub1cc\ub97c \uc9c0\ud0a4\ub294 \uc77c\uc774 \uc5bc\ub9c8\ub098 \uc18c\uc911\ud55c\uc9c0 \ud568\uaed8 \uc0dd\uac01\ud574 \ubcf4\ub824 \ud569\ub2c8\ub2e4.<\/p>\n<h2>\uce58\ub9e4\ub780 \ubb34\uc5c7\uc778\uc9c0 \uba3c\uc800 \uc9da\uc5b4\ubcfc\uac8c\uc694<\/h2>\n<p>\uce58\ub9e4\ub294 \ub2e8\uc77c \uc9c8\ud658\uc774 \uc544\ub2d9\ub2c8\ub2e4. \ub1cc\uc758 \uc2e0\uacbd\uc138\ud3ec\uac00 \uc11c\uc11c\ud788 \uc190\uc0c1\ub418\uba74\uc11c \uae30\uc5b5\ub825, \uc5b8\uc5b4\ub2a5\ub825, \ud310\ub2e8\ub825 \ub4f1 \uc778\uc9c0 \uae30\ub2a5\uc774 \uc800\ud558\ub418\ub294 \uc0c1\ud0dc\ub97c \ud1b5\ud2c0\uc5b4 \uce58\ub9e4\ub77c\uace0 \ubd80\ub985\ub2c8\ub2e4. \uadf8 \uc6d0\uc778\uc5d0 \ub530\ub77c \uc885\ub958\uac00 \ub098\ub258\ub294\ub370, \uac00\uc7a5 \ud754\ud55c \ud615\ud0dc\ub294 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc73c\ub85c \uc804\uccb4 \uce58\ub9e4\uc758 \uc57d 60~70%\ub97c \ucc28\uc9c0\ud569\ub2c8\ub2e4.<\/p>\n<p>\uadf8 \uc678\uc5d0\ub3c4 \ud608\uad00\uc131 \uce58\ub9e4, \ub8e8\uc774\uc18c\uccb4 \uce58\ub9e4, \uc804\ub450\uce21\ub450\uc5fd \uce58\ub9e4 \ub4f1 \ub2e4\uc591\ud55c \uc720\ud615\uc774 \uc788\uc73c\uba70, \uc6d0\uc778\uc5d0 \ub530\ub77c \uc9c4\ud589 \uc18d\ub3c4\uc640 \uc99d\uc0c1\ub3c4 \ub2e4\ub985\ub2c8\ub2e4. \uce58\ub8cc\uc81c \uac1c\ubc1c\uc774 \uc5b4\ub824\uc6e0\ub358 \uc774\uc720 \uc911 \ud558\ub098\ub294 \ubc14\ub85c \uc774 \ubcf5\uc7a1\ud55c \uc6d0\uc778 \uad6c\uc870 \ub54c\ubb38\uc774\uae30\ub3c4 \ud569\ub2c8\ub2e4.<\/p>\n<h2>\uc54c\uce20\ud558\uc774\uba38\ubcd1 \ubc1c\uacac, \uadf8\uac83\uc774 \uc2dc\uc791\uc774\uc5c8\uc2b5\ub2c8\ub2e4<\/h2>\n<p>1906\ub144, \ub3c5\uc77c\uc758 \uc815\uc2e0\uacfc \uc758\uc0ac \uc54c\ub85c\uc774\uc2a4 \uc54c\uce20\ud558\uc774\uba38(Alois Alzheimer)\ub294 \ud55c \ud658\uc790\uc758 \uc0ac\ud6c4 \ub1cc \uc870\uc9c1\uc744 \ubd84\uc11d\ud558\ub2e4\uac00 \ub450 \uac00\uc9c0 \uc774\uc0c1\ud55c \uad6c\uc870\ubb3c\uc744 \ubc1c\uacac\ud569\ub2c8\ub2e4. \ud558\ub098\ub294 \ub1cc\uc138\ud3ec \ubc14\uae65\uc5d0 \uc313\uc778 \ub2e8\ubc31\uc9c8 \ub369\uc5b4\ub9ac, \uc9c0\uae08 \uc6b0\ub9ac\uac00 \uc544\ubc00\ub85c\uc774\ub4dc \ud50c\ub77c\ud06c(amyloid plaque)\ub77c\uace0 \ubd80\ub974\ub294 \uac83\uc774\uc5c8\uace0, \ub2e4\ub978 \ud558\ub098\ub294 \uc138\ud3ec \uc548\uc5d0 \uc5c9\ucf1c \uc788\ub294 \ud0c0\uc6b0(tau) \ub2e8\ubc31\uc9c8 \uc12c\uc720\uc600\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uadf8\ub294 \uc774\uac83\uc774 \ub2e8\uc21c\ud55c \ub178\ud654 \ud604\uc0c1\uacfc \ub2e4\ub974\ub2e4\ub294 \uc0ac\uc2e4\uc744 \uc9c1\uac10\ud588\uace0, \uc774 \ubc1c\uacac\uc740 \ud6d7\ub0a0 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc774\ub77c\ub294 \uc774\ub984\uc73c\ub85c \uc758\ud559\uc0ac\uc5d0 \uae30\ub85d\ub429\ub2c8\ub2e4. \ud558\uc9c0\ub9cc \ub2f9\uc2dc\uc5d0\ub294 \uc774 \ubc1c\uacac\uc774 \ubb34\uc5c7\uc744 \uc758\ubbf8\ud558\ub294\uc9c0 \uc81c\ub300\ub85c \uc774\ud574\ud558\ub294 \uc0ac\ub78c\uc774 \uac70\uc758 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4. \ubcf8\uaca9\uc801\uc778 \uc5f0\uad6c\ub294 \uc218\uc2ed \ub144\uc774 \uc9c0\ub09c \ud6c4\uc5d0\uc57c \uc2dc\uc791\ub429\ub2c8\ub2e4.<\/p>\n<h2>\ucf5c\ub9b0 \uac00\uc124\uacfc \ucd5c\ucd08\uc758 \uce58\ub9e4 \uce58\ub8cc\uc81c \ud0c4\uc0dd<\/h2>\n<p>1970\ub144\ub300\uc5d0 \ub4e4\uc5b4\uc11c\uba74\uc11c \uc5f0\uad6c\uc790\ub4e4\uc740 \uc54c\uce20\ud558\uc774\uba38 \ud658\uc790\uc758 \ub1cc\uc5d0\uc11c \uc544\uc138\ud2f8\ucf5c\ub9b0(acetylcholine)\uc774\ub77c\ub294 \uc2e0\uacbd\uc804\ub2ec\ubb3c\uc9c8\uc774 \ud604\uc800\ud788 \uac10\uc18c\ud574 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud569\ub2c8\ub2e4. \uc544\uc138\ud2f8\ucf5c\ub9b0\uc740 \uae30\uc5b5\uacfc \ud559\uc2b5\uc5d0 \ud575\uc2ec\uc801\uc778 \uc5ed\ud560\uc744 \ud558\ub294 \ubb3c\uc9c8\uc785\ub2c8\ub2e4. \uc774 \ubc1c\uacac\uc744 \uae30\ubc18\uc73c\ub85c \ud55c \uac83\uc774 \ubc14\ub85c \ucf5c\ub9b0 \uac00\uc124(cholinergic hypothesis)\uc785\ub2c8\ub2e4.<\/p>\n<p>\uc774 \uac00\uc124\uc744 \ud1a0\ub300\ub85c \uacfc\ud559\uc790\ub4e4\uc740 \uc544\uc138\ud2f8\ucf5c\ub9b0\uc774 \ubd84\ud574\ub418\ub294 \uac83\uc744 \ub9c9\ub294 \ud6a8\uc18c \uc5b5\uc81c\uc81c \uac1c\ubc1c\uc5d0 \ub098\uc130\uace0, 1993\ub144 \ubbf8\uad6d FDA\ub294 \ud0c0\ud06c\ub9b0(Tacrine)\uc774\ub77c\ub294 \uc57d\ubb3c\uc744 \uc138\uacc4 \ucd5c\ucd08\uc758 \uc54c\uce20\ud558\uc774\uba38 \uce58\ub8cc\uc81c\ub85c \uc2b9\uc778\ud569\ub2c8\ub2e4. \uc644\uc804\ud55c \uce58\ub8cc\ub294 \uc544\ub2c8\uc5c8\uc9c0\ub9cc, \uc99d\uc0c1\uc758 \uc9c4\ud589\uc744 \uc77c\ubd80 \ub2a6\ucd9c \uc218 \uc788\ub2e4\ub294 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc900 \uc5ed\uc0ac\uc801\uc778 \uc21c\uac04\uc774\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uc774\ud6c4 \ub3c4\ub124\ud398\uc9c8(Donepezil), \ub9ac\ubc14\uc2a4\ud2f0\uadf8\ubbfc(Rivastigmine), \uac08\ub780\ud0c0\ubbfc(Galantamine) \ub4f1 \uac19\uc740 \uacc4\uc5f4\uc758 \uac1c\uc120\ub41c \uc57d\ubb3c\ub4e4\uc774 \ucc28\ub840\ub85c \uc2b9\uc778\uc744 \ubc1b\uc558\uace0, \ud604\uc7ac\ub3c4 \ub9ce\uc740 \ud658\uc790\ub4e4\uc5d0\uac8c \uc0ac\uc6a9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<h2>\uc544\ubc00\ub85c\uc774\ub4dc \uac00\uc124\uacfc \uc218\uc2ed \ub144\uc758 \uc2e4\ud328<\/h2>\n<p>\ucf5c\ub9b0 \uac00\uc124 \uae30\ubc18 \uce58\ub8cc\uc81c\ub4e4\uc740 \uc99d\uc0c1\uc744 \uc644\ud654\ud558\ub294 \ub370 \uc77c\ubd80 \ub3c4\uc6c0\uc774 \ub418\uc9c0\ub9cc, \uadfc\ubcf8\uc801\uc778 \uc6d0\uc778\uc744 \ud574\uacb0\ud558\uc9c0\ub294 \ubabb\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub798\uc11c \uc5f0\uad6c\uc790\ub4e4\uc740 \uc54c\uce20\ud558\uc774\uba38\uc758 \ud575\uc2ec \uc6d0\uc778\uc73c\ub85c \uc9c0\ubaa9\ub41c \uc544\ubc00\ub85c\uc774\ub4dc \ud50c\ub77c\ud06c\ub97c \uc81c\uac70\ud558\ub294 \ubc29\ud5a5\uc73c\ub85c \ub208\uc744 \ub3cc\ub838\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uc774\uac83\uc774 \uc544\ubc00\ub85c\uc774\ub4dc \uac00\uc124(amyloid hypothesis)\uc785\ub2c8\ub2e4. \ub1cc\uc5d0 \uc313\uc778 \ubca0\ud0c0 \uc544\ubc00\ub85c\uc774\ub4dc \ub2e8\ubc31\uc9c8\uc774 \uc2e0\uacbd\uc138\ud3ec\ub97c \uc8fd\uc774\uace0 \uce58\ub9e4\ub97c \uc720\ubc1c\ud55c\ub2e4\ub294 \uc774\ub860\uc73c\ub85c, 1990\ub144\ub300 \uc774\ud6c4 \uce58\ub9e4 \uc5f0\uad6c\uc758 \uc8fc\ub958 \ubc29\ud5a5\uc774 \ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uadf8\ub7ec\ub098 \uc774 \uac00\uc124\uc744 \uae30\ubc18\uc73c\ub85c \uac1c\ubc1c\ub41c \uc218\uc2ed \uac1c\uc758 \uc2e0\uc57d \ud6c4\ubcf4\ubb3c\uc9c8\ub4e4\uc740 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \uc904\uc904\uc774 \uc2e4\ud328\ud588\uc2b5\ub2c8\ub2e4. 2000\ub144\ub300\ubd80\ud130 2010\ub144\ub300\uae4c\uc9c0 \uae00\ub85c\ubc8c \uc81c\uc57d\uc0ac\ub4e4\uc774 \uc218\uc870 \uc6d0\uc744 \ud22c\uc790\ud588\uc74c\uc5d0\ub3c4, \uc544\ubc00\ub85c\uc774\ub4dc\ub97c \ud45c\uc801\uc73c\ub85c \ud55c \uc57d\ubb3c\ub4e4\uc740 \uc2e4\uc81c \ud658\uc790\uc5d0\uac8c \uc758\ubbf8 \uc788\ub294 \ud6a8\uacfc\ub97c \ubcf4\uc5ec\uc8fc\uc9c0 \ubabb\ud588\uc2b5\ub2c8\ub2e4. \uacfc\ud559\uacc4\uc5d0\uc11c\ub294 \uc544\ubc00\ub85c\uc774\ub4dc \uac00\uc124 \uc790\uccb4\ub97c \uc7ac\uac80\ud1a0\ud574\uc57c \ud55c\ub2e4\ub294 \ubaa9\uc18c\ub9ac\ub3c4 \ub098\uc654\uc2b5\ub2c8\ub2e4.<\/p>\n<h2>2021\ub144\uacfc 2023\ub144, \uc0c8\ub85c\uc6b4 \uc804\ud658\uc810<\/h2>\n<p>\uae34 \uce68\uccb4\ub97c \uae68\uace0 \uc0c8\ub85c\uc6b4 \uc18c\uc2dd\uc774 \ub4e4\ub824\uc628 \uac83\uc740 2021\ub144\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \ubbf8\uad6d \ubc14\uc774\uc624\uc820(Biogen)\uacfc \uc77c\ubcf8 \uc5d0\uc790\uc774(Eisai)\uac00 \uacf5\ub3d9 \uac1c\ubc1c\ud55c \uc544\ub450\uce74\ub204\ub9d9(Aducanumab)\uc774 FDA\uc758 \uc870\uac74\ubd80 \uc2b9\uc778\uc744 \ubc1b\uc740 \uac83\uc785\ub2c8\ub2e4. \uc544\ubc00\ub85c\uc774\ub4dc\ub97c \uc9c1\uc811 \uc81c\uac70\ud558\ub294 \ubc29\uc2dd\uc758 \uc57d\ubb3c\uc774 \uc2b9\uc778\uc744 \ubc1b\uc740 \uac83 \uc790\uccb4\ub85c \ud070 \ud654\uc81c\uac00 \ub418\uc5c8\uc9c0\ub9cc, \ud6a8\uacfc\uc640 \uc548\uc804\uc131\uc744 \ub458\ub7ec\uc2fc \ub17c\uc7c1\ub3c4 \uc774\uc5b4\uc84c\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uadf8\ub9ac\uace0 2023\ub144, \uac19\uc740 \ub450 \ud68c\uc0ac\uac00 \uac1c\ubc1c\ud55c \ub808\uce74\ub124\ub9d9(Lecanemab, \uc0c1\ud488\uba85 \ub808\ucf10\ube44)\uc774 \uc815\uc2dd FDA \uc2b9\uc778\uc744 \ubc1b\uc73c\uba74\uc11c \ub354\uc6b1 \uc8fc\ubaa9\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc774 \uc57d\ubb3c\uc740 \ucd08\uae30 \uc54c\uce20\ud558\uc774\uba38 \ud658\uc790\uc5d0\uc11c \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558 \uc18d\ub3c4\ub97c \uc57d 27% \ub2a6\ucd94\ub294 \ud6a8\uacfc\ub97c \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \ubcf4\uc600\uace0, \uc544\ubc00\ub85c\uc774\ub4dc \uc81c\uac70 \uc804\ub7b5\uc758 \uac00\ub2a5\uc131\uc744 \ub2e4\uc2dc\uae08 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4. \uc644\uc804\ud55c \uce58\ub8cc\uc81c\ub294 \uc544\ub2c8\uc9c0\ub9cc, \uc218\uc2ed \ub144 \uc2e4\ud328\uc758 \uc5ed\uc0ac\ub97c \ub4a4\ub85c\ud558\uace0 \uc774\ub8ec \uc758\ubbf8 \uc788\ub294 \uc131\uacfc\uc784\uc5d0\ub294 \ubd84\uba85\ud569\ub2c8\ub2e4.<\/p>\n<h2>\uc65c \uce58\ub9e4 \uce58\ub8cc\uc81c \uac1c\ubc1c\uc740 \uc774\ud1a0\ub85d \uc5b4\ub824\uc6b4 \uac78\uae4c\uc694<\/h2>\n<p>\uce58\ub9e4 \uce58\ub8cc\uc81c \uac1c\ubc1c\uc774 \uc720\ub3c5 \ud5d8\ub09c\ud55c \uc774\uc720\uc5d0\ub294 \uba87 \uac00\uc9c0 \uad6c\uc870\uc801\uc778 \uc774\uc720\uac00 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<ul>\n<li>\n<p>\ub1cc\ud608\uad00 \uc7a5\ubcbd(Blood-Brain Barrier): \uc57d\ubb3c\uc774 \ud608\uc561\uc744 \ud1b5\ud574 \ub1cc\uc5d0 \ub3c4\ub2ec\ud558\ub824\uba74 \uc774 \uc7a5\ubcbd\uc744 \ud1b5\uacfc\ud574\uc57c \ud558\ub294\ub370, \ub300\ubd80\ubd84\uc758 \ubb3c\uc9c8\uc740 \uc774\ub97c \ud1b5\uacfc\ud558\uc9c0 \ubabb\ud569\ub2c8\ub2e4.<\/p>\n<\/li>\n<li>\n<p>\uc99d\uc0c1\uc774 \ub098\ud0c0\ub0a0 \ub54c\ub294 \uc774\ubbf8 \ub2a6\uc740 \uacbd\uc6b0\uac00 \ub9ce\uc2b5\ub2c8\ub2e4: \ub1cc\uc138\ud3ec \uc190\uc0c1\uc740 \uc99d\uc0c1\uc774 \ub098\ud0c0\ub098\uae30 \uc218\uc2ed \ub144 \uc804\ubd80\ud130 \uc2dc\uc791\ub418\uae30 \ub54c\ubb38\uc5d0, \uc57d\ubb3c \ud22c\uc5ec \uc2dc\uc810\uc744 \uc815\ud655\ud788 \uc7a1\uae30\uac00 \uc5b4\ub835\uc2b5\ub2c8\ub2e4.<\/p>\n<\/li>\n<li>\n<p>\ub3d9\ubb3c \uc2e4\ud5d8\uacfc \uc778\uccb4 \uc784\uc0c1\uc758 \ucc28\uc774: \uc950\uc5d0\uac8c\uc11c \ud6a8\uacfc\ub97c \ubcf4\uc778 \uc57d\ubb3c\uc774 \uc0ac\ub78c\uc5d0\uac8c\ub294 \uac19\uc740 \ud6a8\uacfc\ub97c \ub0b4\uc9c0 \ubabb\ud558\ub294 \uacbd\uc6b0\uac00 \ub9e4\uc6b0 \ub9ce\uc2b5\ub2c8\ub2e4.<\/p>\n<\/li>\n<li>\n<p>\ubcf5\ud569\uc801\uc778 \uc6d0\uc778: \uce58\ub9e4\ub294 \ub2e8\uc77c\ud55c \uc6d0\uc778\uc774 \uc544\ub2c8\ub77c \uc720\uc804, \uc0dd\ud65c\uc2b5\uad00, \ud658\uacbd \ub4f1 \uc5ec\ub7ec \uc694\uc778\uc774 \ubcf5\uc7a1\ud558\uac8c \uc5bd\ud600 \uc788\uc5b4 \ud558\ub098\uc758 \ubb3c\uc9c8\ub85c \ud574\uacb0\ud558\uae30 \uc5b4\ub835\uc2b5\ub2c8\ub2e4.<\/p>\n<\/li>\n<\/ul>\n<h2>\uce58\ub8cc\uc81c\ub9cc\ud07c \uc911\uc694\ud55c \uac83, \uc608\ubc29\uacfc \uc0dd\ud65c \uad00\ub9ac<\/h2>\n<p>\uce58\ub9e4 \uce58\ub8cc\uc81c\uc758 \uc5ed\uc0ac\ub97c \uc0b4\ud3b4\ubcf4\uba74 \ud55c \uac00\uc9c0 \uc0ac\uc2e4\uc774 \ubd84\uba85\ud574\uc9d1\ub2c8\ub2e4. \ud604\uc7ac\uc758 \uce58\ub8cc\uc81c\ub294 \uc644\uce58\uac00 \uc544\ub2c8\ub77c \uc9c4\ud589\uc744 \ub2a6\ucd94\ub294 \ub370 \uc9d1\uc911\ub418\uc5b4 \uc788\ub2e4\ub294 \uc810\uc785\ub2c8\ub2e4. \uadf8\ub798\uc11c \uc758\ub8cc\uacc4\uc640 \uc5f0\uad6c\uc790\ub4e4\uc774 \uacf5\ud1b5\uc801\uc73c\ub85c \uac15\uc870\ud558\ub294 \uac83\uc774 \ubc14\ub85c \uc608\ubc29\uacfc \uc0dd\ud65c \uc2b5\uad00 \uad00\ub9ac\uc785\ub2c8\ub2e4.<\/p>\n<p>\uc138\uacc4\ubcf4\uac74\uae30\uad6c(WHO)\ub97c \ube44\ub86f\ud55c \uc5ec\ub7ec \uae30\uad00\uc758 \ubcf4\uace0\uc5d0 \ub530\ub974\uba74, \uaddc\uce59\uc801\uc778 \uc2e0\uccb4 \ud65c\ub3d9, \uade0\ud615 \uc7a1\ud78c \uc2dd\uc2b5\uad00, \ud608\uc555\uacfc \ud608\ub2f9 \uad00\ub9ac, \ucda9\ubd84\ud55c \uc218\uba74, \uc0ac\ud68c\uc801 \ud65c\ub3d9 \uc720\uc9c0 \ub4f1\uc774 \uce58\ub9e4 \ubc1c\uc0dd \uc704\ud5d8\uc744 \ub0ae\ucd94\ub294 \ub370 \uc2e4\uc9c8\uc801\uc778 \ub3c4\uc6c0\uc774 \ub41c\ub2e4\uace0 \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc758\ud559\uc801 \ucc98\ubc29\uc774 \uc544\ub2c8\ub77c \ucc38\uace0 \uc815\ubcf4\ub85c \ubc1b\uc544\ub4e4\uc774\uc2dc\uace0, \uac1c\uc778\uc758 \uac74\uac15 \uc0c1\ud0dc\uc5d0 \ub9de\uac8c \uc804\ubb38\uac00\uc640 \uc0c1\ub2f4\ud558\uc2dc\ub294 \uac83\uc744 \uad8c\ud574\ub4dc\ub9bd\ub2c8\ub2e4.<\/p>\n<p>\ud2b9\ud788 \ud608\uad00 \uac74\uac15\uc740 \ub1cc \uac74\uac15\uacfc \ub9e4\uc6b0 \ubc00\uc811\ud558\uac8c \uc5f0\uacb0\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4. \ud608\uad00\uc131 \uce58\ub9e4\uac00 \uc804\uccb4 \uce58\ub9e4\uc758 \uc0c1\ub2f9 \ubd80\ubd84\uc744 \ucc28\uc9c0\ud558\ub294 \ub9cc\ud07c, \ud608\uad00\uc744 \uac74\uac15\ud558\uac8c \uc720\uc9c0\ud558\ub294 \uc77c\uc774 \ub1cc\ub97c \uc9c0\ud0a4\ub294 \uae30\ucd08\uac00 \ub429\ub2c8\ub2e4. 30\ub300\ubd80\ud130 \ud608\uad00\uacfc \ud53c\ub85c \uad00\ub9ac\uc5d0 \uad00\uc2ec\uc744 \uac16\uae30 \uc2dc\uc791\ud558\ub294 \uac83\uc774 \uc911\uc694\ud558\ub2e4\ub294 \uc810\uc744 \ub9ce\uc740 \uc804\ubb38\uac00\ub4e4\uc774 \uc774\uc57c\uae30\ud569\ub2c8\ub2e4.<\/p>\n<h2>FAQ: \uce58\ub9e4 \uce58\ub8cc\uc81c\uc5d0 \ub300\ud574 \uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38<\/h2>\n<h3>Q. \uce58\ub9e4\ub294 \uc9c0\uae08 \uc644\uce58\uac00 \uac00\ub2a5\ud55c\uac00\uc694?<\/h3>\n<p>\ud604\uc7ac\uae4c\uc9c0 \uce58\ub9e4\ub97c \uc644\uc804\ud788 \uce58\ub8cc\ud558\ub294 \uc57d\ubb3c\uc740 \uc874\uc7ac\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ud604\uc7ac \uc2b9\uc778\ub41c \uce58\ub8cc\uc81c\ub4e4\uc740 \uc99d\uc0c1\uc758 \uc9c4\ud589\uc744 \ub2a6\ucd94\uac70\ub098 \uc77c\ubd80 \uc778\uc9c0 \uae30\ub2a5\uc744 \uc77c\uc2dc\uc801\uc73c\ub85c \uc720\uc9c0\ud558\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc8fc\ub294 \uc218\uc900\uc785\ub2c8\ub2e4. \ub2e4\ub9cc \uc5f0\uad6c\ub294 \uc9c0\uc18d\uc801\uc73c\ub85c \ubc1c\uc804\ud558\uace0 \uc788\uc73c\uba70, \uc870\uae30 \uc9c4\ub2e8\uacfc \ucd08\uae30 \uac1c\uc785\uc774 \ub9e4\uc6b0 \uc911\uc694\ud558\ub2e4\uace0 \uc758\ub8cc\uacc4\ub294 \uac15\uc870\ud569\ub2c8\ub2e4.<\/p>\n<h3>Q. \uc80a\uc744 \ub54c\ubd80\ud130 \ub1cc \uac74\uac15\uc744 \ucc59\uaca8\uc57c \ud558\ub098\uc694?<\/h3>\n<p>\ub124, \ub9ce\uc740 \uc5f0\uad6c\uc5d0\uc11c \ub1cc\uc138\ud3ec \uc190\uc0c1\uc740 \uc99d\uc0c1\uc774 \ub098\ud0c0\ub098\uae30 20~30\ub144 \uc804\ubd80\ud130 \uc11c\uc11c\ud788 \uc9c4\ud589\ub41c\ub2e4\uace0 \ubcf4\uace0\ud569\ub2c8\ub2e4. 40\ub300, 50\ub300\uc5d0 \uc99d\uc0c1\uc774 \ub098\ud0c0\ub0ac\ub2e4\uba74 \ub1cc\uc758 \ubcc0\ud654\ub294 \uc774\ubbf8 \uadf8 \ud6e8\uc52c \uc774\uc804\ubd80\ud130 \uc2dc\uc791\ub41c \uacbd\uc6b0\uac00 \ub9ce\uc2b5\ub2c8\ub2e4. 30\ub300\ubd80\ud130 \ud608\uad00 \uac74\uac15, \uaddc\uce59\uc801\uc778 \uc6b4\ub3d9, \uc218\uba74 \uad00\ub9ac \ub4f1 \uc0dd\ud65c \uc2b5\uad00\uc5d0 \uad00\uc2ec\uc744 \uac16\ub294 \uac83\uc774 \uc911\uc694\ud55c \uc774\uc720\uc785\ub2c8\ub2e4.<\/p>\n<h3>Q. \uce58\ub9e4 \uce58\ub8cc\uc81c\uc640 \uac74\uac15\uae30\ub2a5\uc2dd\ud488\uc740 \ub2e4\ub978 \uac74\uac00\uc694?<\/h3>\n<p>\ub124, \uc804\ud600 \ub2e4\ub985\ub2c8\ub2e4. \uce58\ub9e4 \uce58\ub8cc\uc81c\ub294 \uc784\uc0c1\uc2dc\ud5d8\uc744 \ud1b5\ud574 \ud6a8\uacfc\uc640 \uc548\uc804\uc131\uc774 \uac80\uc99d\ub41c \uc758\uc57d\ud488\uc73c\ub85c, \ubc18\ub4dc\uc2dc \uc758\uc0ac\uc758 \ucc98\ubc29\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \uac74\uac15\uae30\ub2a5\uc2dd\ud488\uc740 \uc2e0\uccb4\uc758 \uc815\uc0c1\uc801\uc778 \uae30\ub2a5 \uc720\uc9c0\uc640 \uac74\uac15 \uc99d\uc9c4\uc744 \ubaa9\uc801\uc73c\ub85c \ud558\ub294 \uac83\uc73c\ub85c, \ud2b9\uc815 \uc9c8\ubcd1\uc758 \uce58\ub8cc\ub098 \uc608\ubc29\uc744 \ubaa9\uc801\uc73c\ub85c \ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ub450 \uac00\uc9c0\ub97c \ud63c\ub3d9\ud558\uc9c0 \uc54a\uc73c\uc2dc\ub294 \uac83\uc774 \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n<h2>\uac74\uac15\ud55c \uc624\ub298\uc774 \ub0b4\uc77c\uc758 \ub1cc\ub97c \ub9cc\ub4ed\ub2c8\ub2e4<\/h2>\n<p>\uce58\ub9e4 \uce58\ub8cc\uc81c\uc758 \uc5ed\uc0ac\ub294 \ud3ec\uae30\ud558\uc9c0 \uc54a\ub294 \uacfc\ud559\uc758 \uc5ed\uc0ac\uc774\uae30\ub3c4 \ud558\uc9c0\ub9cc, \ub3d9\uc2dc\uc5d0 \uc608\ubc29\uc774 \uc5bc\ub9c8\ub098 \uc18c\uc911\ud55c\uc9c0\ub97c \uc77c\uae68\uc6cc \uc8fc\ub294 \uc774\uc57c\uae30\uc774\uae30\ub3c4 \ud569\ub2c8\ub2e4. \uc644\ubcbd\ud55c \uce58\ub8cc\uc81c\uac00 \ub098\uc624\uae30\ub97c \uae30\ub2e4\ub9ac\uae30\ubcf4\ub2e4\ub294, \uc9c0\uae08 \uc774 \uc21c\uac04 \uc6b0\ub9ac\uac00 \uc2e4\ucc9c\ud560 \uc218 \uc788\ub294 \uac74\uac15\ud55c \uc0dd\ud65c \uc2b5\uad00\uc744 \ud558\ub098\uc529 \uc313\uc544\uac00\ub294 \uac83\uc774 \uac00\uc7a5 \ud604\uc2e4\uc801\uc774\uace0 \uac15\ub825\ud55c \ub1cc \uac74\uac15 \uc804\ub7b5\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\ub108\ub450\ub098\ub3c4 \uac74\uac15\ud55c \ub098\ud22c\ub77c\ube44\ud0c8\ub9ac\uc2a4\ub294 30\ub300\ubd80\ud130 50\ub300\uae4c\uc9c0 \uac74\uac15\ud55c \uc0b6\uc744 \ud568\uaed8 \uace0\ubbfc\ud558\ub294 \uacf5\uac04\uc785\ub2c8\ub2e4. \ud608\uad00 \uac74\uac15, \ud53c\ub85c \ud68c\ubcf5, \ud53c\ubd80 \uad00\ub9ac\ucc98\ub7fc \ub9e4\uc77c\uc758 \uc0b6\uc5d0\uc11c \uc2e4\ucc9c\ud560 \uc218 \uc788\ub294 \uac74\uac15 \uc815\ubcf4\uc640 \uc774\uc57c\uae30\ub4e4\uc744 \ub098\ub204\uace0 \uc788\uc73c\ub2c8, \uad00\uc2ec \uc788\uc73c\uc2e0 \ubd84\ub4e4\uc740 \ub124\uc774\ubc84 \uce74\ud398\uc5d0\uc11c \ud3b8\ud558\uac8c \ud568\uaed8\ud574 \uc8fc\uc138\uc694.<\/p>\n<p>\uac74\uac15\ud55c \uc815\ubcf4\uc640 \ub530\ub73b\ud55c \uc774\uc57c\uae30\uac00 \uae30\ub2e4\ub9ac\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc544\ub798 \ub9c1\ud06c\uc5d0\uc11c \uac00\uc785\ud558\uc2dc\uba74 \ub2e4\uc591\ud55c \uac74\uac15 \uc815\ubcf4\uc640 \ucee4\ubba4\ub2c8\ud2f0\ub97c \ub9cc\ub098\ubcf4\uc2e4 \uc218 \uc788\uc5b4\uc694.<\/p>\n<p><a target=\"_blank\" rel=\"noopener\" href=\"https:\/\/cafe.naver.com\/pinksxwo8\">\ub108\ub450\ub098\ub3c4 \uac74\uac15\ud55c \uce74\ud398 \ubc14\ub85c\uac00\uae30<\/a><\/p>\n<p>\uc624\ub298\ub3c4 \uac74\uac15\ud55c \ud558\ub8e8 \ub418\uc2dc\uae38 \ubc14\ub78d\ub2c8\ub2e4. \uc791\uc740 \uc2b5\uad00 \ud558\ub098\uac00 10\ub144 \ud6c4\uc758 \ub1cc\ub97c \ubc14\uafc0 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\uce58\ub9e4 \uce58\ub8cc\uc81c\uc758 \ud0c4\uc0dd\uc740 \uc218\uc2ed \ub144\uc5d0 \uac78\uce5c \ub1cc\uacfc\ud559 \uc5f0\uad6c\uc640 \uc2e4\ud328\ub97c \ub51b\uace0 \uc774\ub8e8\uc5b4\uc9c4 \uacfc\ud559\uc801 \uc5ec\uc815\uc758 \uacb0\uacfc\uc774\uba70, \uadf8 \uc5ed\uc0ac\ub97c \uc774\ud574\ud558\uba74 \ub1cc \uac74\uac15\uc744 \uc9c0\ud0a4\ub294 \uc0dd\ud65c \uc2b5\uad00\uc758 \uc911\uc694\uc131\uc744 \ub354 \uae4a\uc774 \ub290\ub084 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n","protected":false},"author":14,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","najm_jsonld":"","footnotes":""},"categories":[4],"tags":[],"class_list":["post-33","post","type-post","status-publish","format-standard","hentry","category-4"],"_links":{"self":[{"href":"https:\/\/naturavitalis.blog.rankrogic.com\/wp-json\/wp\/v2\/posts\/33","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/naturavitalis.blog.rankrogic.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/naturavitalis.blog.rankrogic.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/naturavitalis.blog.rankrogic.com\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/naturavitalis.blog.rankrogic.com\/wp-json\/wp\/v2\/comments?post=33"}],"version-history":[{"count":1,"href":"https:\/\/naturavitalis.blog.rankrogic.com\/wp-json\/wp\/v2\/posts\/33\/revisions"}],"predecessor-version":[{"id":36,"href":"https:\/\/naturavitalis.blog.rankrogic.com\/wp-json\/wp\/v2\/posts\/33\/revisions\/36"}],"wp:attachment":[{"href":"https:\/\/naturavitalis.blog.rankrogic.com\/wp-json\/wp\/v2\/media?parent=33"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/naturavitalis.blog.rankrogic.com\/wp-json\/wp\/v2\/categories?post=33"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/naturavitalis.blog.rankrogic.com\/wp-json\/wp\/v2\/tags?post=33"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}